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브로모에탄올

브로모에탄올

CAS NO.: 540-51-2

콘텐츠:98.00%

응용 분야: 피페리딘과의 반응을 통해 2-피페리딘-1-일-에탄올과 같은 의약품 합성을 위한 빌딩 블록으로 사용되며, PcFe(II)/NaBH₄ 등의 촉매 시스템을 사용하여 니트로아렌을 선택적으로 환원하는 데에도 사용됩니다.

설명

제품 개요

2-Bromoethanol (also known as Ethylene Bromohydrin or Bromoethanol),, CAS No.: 540-51-2 , with the chemical formula C₂H₅BrO and a molecular weight of 124.96 g/mol. It is a colorless to pale yellow or dark brown hygroscopic liquid with a sweet, burning taste and relatively stable chemical properties, though it is toxic. This compound belongs to the class of halo alcohols and is primarily used in organic synthesis and industrial processes.

속성

2-Bromoethanol exhibits the following key physical and chemical properties:

  • 물리적 상태: 액체(실온에서).
  • 모양: Colorless to pale yellow or dark brown liquid.
  • Odor/Taste: Mild odor; sweet, burning taste.
  • 녹는점: Not widely reported (typically low, around -50 °C based on similar compounds).
  • 끓는점: Approximately 150 °C (decomposes partially).
  • 밀도: 1.59–1.60 g/mL (at 20 °C).
  • 용해성: Miscible with water (forms an azeotrope); soluble in organic solvents like ethanol and ether.
  • 안정성: Relatively stable but hygroscopic; incompatible with strong oxidants, acids, and bases; may decompose upon heating.
  • 독성: Toxic by ingestion, inhalation, and skin absorption; causes irritation to skin, eyes, and respiratory tract; classified as a hazardous substance (UN 1566, corrosive and toxic).

애플리케이션

The primary applications of 2-bromoethanol include:

  • 유기 합성 중간체: Used as a building block for synthesizing pharmaceuticals, such as 2-piperidin-1-yl-ethanol via reaction with piperidine; also in selective reduction of nitroarenes using catalyst systems like PcFe(II)/NaBH₄.
  • 솔벤트: Acts as a solvent and raw material in various organic reactions and chemical experiments.
  • Industrial Processes: Employed in the production of surfactants, pharmaceuticals, and other fine chemicals; historically involved in ethylene oxide reactions with hydrobromic acid, leading to potential exposure risks in manufacturing.
  • 기타: Used in laboratory settings for bromoalkylation reactions and as a reagent in polymer chemistry.

분류

The following table outlines the classification of 2-bromoethanol based on chemical properties, uses, and regulations:

분류 유형 특정 카테고리 설명
화학 등급 헤일로 알코올(브로모히드린) A β-bromo alcohol derivative of ethylene glycol, reactive in nucleophilic substitutions and prone to forming epoxides.
사용 클래스 유기 합성 시약/용매 Primarily an intermediate for pharmaceutical and fine chemical production; limited commercial use due to toxicity.
위험 등급 Toxic Liquid (UN 1566); Corrosive Toxic (GHS: Acute Tox. 3, Skin Corr. 1B); irritant and corrosive; handle with protective equipment.
규제 등급 Hazardous Substance (REACH, TSCA) Registered under EU REACH and US TSCA; subject to environmental and workplace exposure controls.

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