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CAS NO.: 540-51-2

Содержание:98.00%

Применение: Используется в качестве строительного блока для синтеза фармацевтических препаратов, таких как 2-пиперидин-1-ил-этанол по реакции с пиперидином; также в селективном восстановлении нитроаренов с помощью каталитических систем, таких как PcFe(II)/NaBH₄. и т.д..

Описание

Обзор продукции

2-Bromoethanol (also known as Ethylene Bromohydrin or Bromoethanol),, CAS No.: 540-51-2 , with the chemical formula C₂H₅BrO and a molecular weight of 124.96 g/mol. It is a colorless to pale yellow or dark brown hygroscopic liquid with a sweet, burning taste and relatively stable chemical properties, though it is toxic. This compound belongs to the class of halo alcohols and is primarily used in organic synthesis and industrial processes.

Свойства

2-Bromoethanol exhibits the following key physical and chemical properties:

  • Физическое состояние: Жидкость (при комнатной температуре).
  • Внешний вид: Colorless to pale yellow or dark brown liquid.
  • Odor/Taste: Mild odor; sweet, burning taste.
  • Температура плавления: Not widely reported (typically low, around -50 °C based on similar compounds).
  • Температура кипения: Approximately 150 °C (decomposes partially).
  • Плотность: 1.59–1.60 g/mL (at 20 °C).
  • Растворимость: Miscible with water (forms an azeotrope); soluble in organic solvents like ethanol and ether.
  • Стабильность: Relatively stable but hygroscopic; incompatible with strong oxidants, acids, and bases; may decompose upon heating.
  • Токсичность: Toxic by ingestion, inhalation, and skin absorption; causes irritation to skin, eyes, and respiratory tract; classified as a hazardous substance (UN 1566, corrosive and toxic).

Приложения

The primary applications of 2-bromoethanol include:

  • Промежуточный продукт органического синтеза: Used as a building block for synthesizing pharmaceuticals, such as 2-piperidin-1-yl-ethanol via reaction with piperidine; also in selective reduction of nitroarenes using catalyst systems like PcFe(II)/NaBH₄.
  • Растворитель: Acts as a solvent and raw material in various organic reactions and chemical experiments.
  • Industrial Processes: Employed in the production of surfactants, pharmaceuticals, and other fine chemicals; historically involved in ethylene oxide reactions with hydrobromic acid, leading to potential exposure risks in manufacturing.
  • Другие: Used in laboratory settings for bromoalkylation reactions and as a reagent in polymer chemistry.

Классификация

The following table outlines the classification of 2-bromoethanol based on chemical properties, uses, and regulations:

Тип классификации Конкретная категория Описание
Химический класс Галоидный спирт (бромогидрин) A β-bromo alcohol derivative of ethylene glycol, reactive in nucleophilic substitutions and prone to forming epoxides.
Класс использования Реагент/растворитель для органического синтеза Primarily an intermediate for pharmaceutical and fine chemical production; limited commercial use due to toxicity.
Класс опасности Toxic Liquid (UN 1566); Corrosive Toxic (GHS: Acute Tox. 3, Skin Corr. 1B); irritant and corrosive; handle with protective equipment.
Регуляторный класс Hazardous Substance (REACH, TSCA) Registered under EU REACH and US TSCA; subject to environmental and workplace exposure controls.

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