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1-Bromo-4-pentène (CAS NO. : 1119-51-3)

1-Bromo-4-pentène (CAS NO. : 1119-51-3)

N° CAS : 1119-51-3

Contenu:98.00%

Application : Utilisé dans la synthèse stéréosélective du 7α-(3-carboxypropyl) estradiol, la préparation de thioacétates comme ceux des dérivés de l'acide sialique, et les synthèses récentes de la DL-histrionicotoxine et des acides gras contenant de la benzophénone, etc.

Description

Aperçu du produit

1-Bromo-4-pentene (also known as 5-Bromo-1-penteneor 4-Pentenyl bromide) CAS No.: 1119-51-3 , with the chemical formula C₅H₉Br and a molecular weight of 149.03 g/mol. It is a clear colorless to light yellow liquid. This compound belongs to the class of alkyl halides with an alkene group and is primarily used in organic synthesis and as a reagent, though it is subject to safety regulations due to its flammable and irritant properties.

Propriétés

5-Bromo-1-pentene exhibits the following key physical and chemical properties:

  • État physique: Liquide (à température ambiante).
  • Apparence: Liquide clair, incolore à jaune clair.
  • Odeur: Non spécifié.
  • Point de fusion: -106.7 °C (estimate).
  • Point d'ébullition: 126-127 °C at 765 mmHg (lit.).
  • Densité: 1.258 g/mL at 25 °C (lit.).
  • Solubilité: Insoluble in water; soluble in organic solvents like chloroform, ethanol, and ether.
  • Stabilité: Stable under normal conditions; incompatible with strong oxidizing agents; flammable.
  • Toxicité: Moderately toxic; causes skin irritation, eye irritation, and respiratory irritation; may cause dizziness, nausea, and central nervous system effects upon inhalation.

Applications

The primary applications of 5-bromo-1-pentene include:

  • Intermédiaire de synthèse organique: Used in the stereoselective synthesis of 7α-(3-carboxypropyl) estradiol, preparation of thioacetates like those in sialic acid derivatives, and recent syntheses of DL-histrionicotoxin and benzophenone-containing fatty acids.
  • Réactif: Employed in the production of pharmaceuticals, agrochemicals, fragrances, polymers, and as an analytical reagent.
  • Autres: Serves as a versatile building block in organic chemistry for introducing alkyl chains with functional groups.

Classification

The following table outlines the classification of 5-bromo-1-pentene based on chemical properties, uses, and regulations:

Type de classification Catégorie spécifique Description
Classe chimique Alkyl Halide (Bromoalkene) An unsaturated bromoalkane, reactive in nucleophilic substitution and addition reactions.
Classe d'utilisation Réactif de synthèse organique/Intermédiaire Principalement utilisé comme réactif et intermédiaire dans la synthèse chimique.
Classe de danger Flammable Liquid (UN 1993); Irritant Flammable (H225, flash point ~31 °C); skin irritant (H315), eye irritant (H319), respiratory irritant (H335); Packing Group III.
Classe réglementaire Produit chimique contrôlé (REACH, TSCA) Listed under EU REACH and US TSCA; subject to environmental and safety controls (WGK 3 in Germany).

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