{"id":3220,"date":"2025-08-28T16:39:08","date_gmt":"2025-08-28T08:39:08","guid":{"rendered":"https:\/\/www.honorpigments.com\/?post_type=product&#038;p=3220"},"modified":"2025-09-22T09:55:50","modified_gmt":"2025-09-22T01:55:50","slug":"nn-diizopropylethylamin","status":"publish","type":"product","link":"https:\/\/www.honorpigment.com\/cs\/produkt\/nn-diizopropylethylamin\/","title":{"rendered":"N,N-diizopropylethylamin (CAS NO.: 7087-68-5)"},"content":{"rendered":"<h3 dir=\"auto\">Product Overview<\/h3>\n<p dir=\"auto\"><strong>N,N-Diisopropylethylamine<\/strong> (also known as DIPEA, N-Ethyldiisopropylamine, or Ethyldiisopropylamine) CAS No.: 7087-68-5 , with the chemical formula C\u2088H\u2081\u2089N and a molecular weight of 129.24 g\/mol. It is a colorless liquid with an amine-like odor. This compound belongs to the class of tertiary amines and is primarily used as a non-nucleophilic base in organic synthesis, though it is subject to safety regulations due to its flammable, corrosive, and irritant properties.<\/p>\n<h3 dir=\"auto\">Properties<\/h3>\n<p dir=\"auto\">N,N-Diisopropylethylamine exhibits the following key physical and chemical properties:<\/p>\n<ul dir=\"auto\">\n<li><strong>Physical State<\/strong>: Liquid (at room temperature).<\/li>\n<li><strong>Appearance<\/strong>: Colorless to pale yellow liquid.<\/li>\n<li><strong>Odor<\/strong>: Amine-like.<\/li>\n<li><strong>Melting Point<\/strong>: -50 to -46 \u00b0C.<\/li>\n<li><strong>Boiling Point<\/strong>: 126-127 \u00b0C.<\/li>\n<li><strong>Density<\/strong>: 0.742 g\/mL (at 25 \u00b0C).<\/li>\n<li><strong>Solubility<\/strong>: Slightly soluble in water (4.01 g\/L at 20 \u00b0C); miscible with organic solvents like ethanol and ether.<\/li>\n<li><strong>Stability<\/strong>: Stable under normal conditions; incompatible with strong acids, oxidizing agents, and acid chlorides; hygroscopic.<\/li>\n<li><strong>Toxicity<\/strong>: Moderately toxic; acute toxicity by inhalation (Category 3) and oral (Category 4); causes severe eye damage (Category 1), skin and respiratory irritation; target organ is the respiratory system.<\/li>\n<\/ul>\n<h3 dir=\"auto\">Aplikace<\/h3>\n<p dir=\"auto\">The primary applications of N,N-Diisopropylethylamine include:<\/p>\n<ul dir=\"auto\">\n<li><strong>Organic Synthesis Intermediate<\/strong>: Used as a non-nucleophilic base in reactions such as peptide coupling, alkylation, enolboration, and Pd(0)-catalyzed alkoxycarbonylation; acts as a proton scavenger and activator for chiral catalysts.<\/li>\n<li><strong>Reagent<\/strong>: Employed in the synthesis of pharmaceuticals (e.g., mannosylated ovalbumin peptides), marine toxins like Gambierol, indenopyrones, and vinyl sulfones; investigated in lipase-catalyzed syntheses and hydrogenation processes.<\/li>\n<li><strong>Other<\/strong>: Serves as a catalyst and base in various organic reactions, including substitution reactions and the preparation of fine chemicals.<\/li>\n<\/ul>\n<h3 dir=\"auto\">Klasifikace<\/h3>\n<p dir=\"auto\">The following table outlines the classification of N,N-Diisopropylethylamine based on chemical properties, uses, and regulations:<\/p>\n<div dir=\"auto\">\n<div>\n<div><\/div>\n<\/div>\n<table dir=\"auto\" data-wide=\"false\">\n<thead>\n<tr>\n<th data-col-size=\"sm\">Classification Type<\/th>\n<th data-col-size=\"lg\">Specific Category<\/th>\n<th data-col-size=\"xl\">Popis<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td data-col-size=\"sm\"><strong>Chemical Class<\/strong><\/td>\n<td data-col-size=\"lg\">Tertiary Amine<\/td>\n<td data-col-size=\"xl\">A sterically hindered amine, non-nucleophilic and used as a base in organic chemistry.<\/td>\n<\/tr>\n<tr>\n<td data-col-size=\"sm\"><strong>Usage Class<\/strong><\/td>\n<td data-col-size=\"lg\">Organic Synthesis Reagent\/Base<\/td>\n<td data-col-size=\"xl\">Primarily a non-nucleophilic base and reagent in laboratory and industrial synthesis.<\/td>\n<\/tr>\n<tr>\n<td data-col-size=\"sm\"><strong>Hazard Class<\/strong><\/td>\n<td data-col-size=\"lg\">Flammable Liquid (UN 1993); Corrosive; Toxic<\/td>\n<td data-col-size=\"xl\">Flammable (Category 2, flash point 9.5 \u00b0C); acute toxic (inhalation Category 3, oral Category 4); eye damage (Category 1); irritant (skin, respiratory); aquatic chronic (Category 2).<\/td>\n<\/tr>\n<tr>\n<td data-col-size=\"sm\"><strong>Regulatory Class<\/strong><\/td>\n<td data-col-size=\"lg\">Controlled Chemical (REACH, TSCA, CLP)<\/td>\n<td data-col-size=\"xl\">Listed under EU REACH, US TSCA, and CLP regulations; WGK 2 in Germany; subject to environmental release controls and hazardous substance handling.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u010c. CAS: 7087-68-5<\/p>\n<p>Obsah:99.00%<\/p>\n<p>Pou\u017eit\u00ed: Pou\u017e\u00edv\u00e1 se jako nenukleofiln\u00ed b\u00e1ze v reakc\u00edch, jako je peptidov\u00e1 vazba, alkylace, enolborace a Pd(0)-katalyzovan\u00e1 alkoxykarbonylace; p\u016fsob\u00ed jako vychyt\u00e1va\u010d proton\u016f a aktiv\u00e1tor pro chir\u00e1ln\u00ed katalyz\u00e1tory atd.<\/p>","protected":false},"featured_media":3250,"template":"","meta":[],"product_brand":[],"product_cat":[86],"product_tag":[102,104,103,101],"class_list":{"0":"post-3220","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-brominated-compounds-and-derivatives","7":"product_tag-dipea","8":"product_tag-ethyldiisopropylamine","9":"product_tag-n-ethyldiisopropylamine","10":"product_tag-nn-diisopropylethylamine","11":"stm_brands-honor-intermediates","13":"first","14":"instock","15":"shipping-taxable","16":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/www.honorpigment.com\/cs\/wp-json\/wp\/v2\/product\/3220","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.honorpigment.com\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.honorpigment.com\/cs\/wp-json\/wp\/v2\/types\/product"}],"version-history":[{"count":0,"href":"https:\/\/www.honorpigment.com\/cs\/wp-json\/wp\/v2\/product\/3220\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.honorpigment.com\/cs\/wp-json\/wp\/v2\/media\/3250"}],"wp:attachment":[{"href":"https:\/\/www.honorpigment.com\/cs\/wp-json\/wp\/v2\/media?parent=3220"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.honorpigment.com\/cs\/wp-json\/wp\/v2\/product_brand?post=3220"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.honorpigment.com\/cs\/wp-json\/wp\/v2\/product_cat?post=3220"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.honorpigment.com\/cs\/wp-json\/wp\/v2\/product_tag?post=3220"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}